| Bioactivity | [D-p-Cl-Phe6,Leu17]-VIP TFA is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP TFA has no activity on glucagon, secretin or GRF receptors[1][2][3]. | ||||||
| Name | [D-p-Cl-Phe6,Leu17]-VIP TFA | ||||||
| Sequence | His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 | ||||||
| Shortening | HSDAV-{Cl-Phe}-TDNYTRLRKQLAVKKYLNSILN-NH2 | ||||||
| Formula | C150H240F3ClN44O44 | ||||||
| Molar Mass | 3456.22 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
[D-p-Cl-Phe6,Leu17]-VIP TFA
CAS: F: C150H240F3ClN44O44 W: 3456.22
-VIP TFA is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125
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